Health analyses: the basic principles

Health analyses: the basic principles

As the success of your research work is directly related to the stability and the reliability of the experimental model being used, it is imperative that we, at JANVIER LABS, guarantee animals which are in first class health. To assure you of objectivity and non-bias of results, all our analyses are carried out by independent laboratories, in accordance with techniques which are standardised and validated against international benchmarks. Based on the FELASA recommendations, JANVIER LABS health policy enables the precise health status of our animal colonies to be known. 

Technical analysis: 2 characterising criteria

The technical analysis is evaluated according to 2 criteria: the sensitivity and the specificity. Dependent on the germ researched, the accredited and approved laboratories with which JANVIER LABS works, use a standardised method, validated against international benchmarks. Whether, for example, it is a PCR (Polymerase Chain Reaction), an ELISA (Enzyme Linked ImmunoSorbent Assay) or an IFA (Immunofluorescence assay), each technique has its own characteristics. Thus, depending on the method used, the target screening can be precise:

  • For a PCR method, for example, it is the pathogen which is sought. This comprises a direct and very specific research, which can generate false negatives;
  • Conversely, for an ELISA method, it is the trace of the passage of the pathogen which is sought. This comprises a more sensitive method, which can lead to false positives.

Also, in the case of positive results, one of the rules to confirm the result is to use another method, with a different sensitivity or specificity. If an alternative method does not exist, then it is recommended to conduct the tests in another laboratory. The aim is to have a different analysis, so as not to repeat the unidentified bias.

Laboratory analyses: an external and independent benchmark

If the technique is a key routine control element and is to confirm or reject a result, the laboratory conducting the analyses is an equally important component of the reliability of the results. JANVIER LABS works with external laboratories, such as BioDoc or IDEXX BioResearch Europe in Germany, QM Diagnostics in the Netherlands or the LDA 53 in France. These laboratories are:

  • Independent external laboratories, signalling non-bias results   
  • Well known, signalling objective results
  • and accredited or approved by accreditors (COFRAC for France, DAkkS for Germany or CCKL for the Netherlands), signalling reliability in the methods used.

Frequency of controls

At JANVIER LABS, the frequency of the health checks is 6 weeks, while FELASA recommends a frequency of checks every 13 weeks.


Our health statements provide you with all the information on: the germs researched, the name of the laboratory which conducted the checks, the technique used and historical data. You can find health statements on our website for each research model.


As an international expert in the production of rodents and associated services for Biomedical Research, the objective of JANVIER LABS is to provide the animals you need for your research programmes.

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