Laboratory services

List of laboratory services

Excision and ligation surgery

Species and characteristics of the models:

All species from 4 weeks of age; for younger animals, please contact us.

Description of our service

Excision surgery involves complete or partial removal of an organ. This technique allows the study of the influence of an organ on the physiology of healthy animals or in a diseased animal. Excision surgery is also a method for inducing a disease model such as the 5/6 nephrectomy model of renal failure in rats.

The ligation aims to block a biological flow both in the circulatory system (ligation of a vein, for example) and from organ to organ (ligation of the ureter for example). Ligation is primarily used for the induction of disease models or for the control of reproduction.

Excision surgery:

  • Ovariectomy
  • Ovario-hysterectomy
  • Splenectomy
  • Vasectomy
  • Castration
  • 70% hepatectomy
  • Bilateral diaphragmatic vagotomy
  • Nephrectomy (unilateral or 5/6)
  • Adrenalectomy
  • Thyroido-parathyroidectomy

Ligation surgery:

  • Tubal ligation
  • Ureter ligation
  • For other types of ligation, please contact us.

Our method

The surgeries are performed under anesthesia with the combined use of anesthetic and analgesic (a2-adrenergic receptor agonist) drugs.

Management of postoperative pain is made by systematic use of NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).

Possible options

  • Sham surgeries.
  • Inclusion of surgery in a protocol.
  • Combination of surgery with placement of vascular catheters.
  • Procedural guide for perioperative care.
  • Performing surgery with a SOPF status.

Our added value

  • Traceability of interventions.
  • Specific perioperative care for each type of surgery.
  • Optimal conditions of the operated animals during shipments, thanks to our dedicated and internal transport service.
  • Ethical review process by our IACUC (MESR No. 078).

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