Research models

List of models

Nomenclature: CSJLF1/JRj

Type: Hybrid mouse
Colour and related genotype: Agouti mouse - A/A, B/b, Tyrc/Tyrc MHC: Haplotype H2d/s
Origin: from ♀ BALB/cJRj and ♂ SJL/JRj (from JANVIER LABS)
Breeding: Easy to rear, good maternal instinct

Fields of research

  • Genetic
  • Transgenesis
  • Transplantation

Description of our model

These F1 hybrids are the result of a cross between a BALB/cJRj female and a SJL/JRj male. F1 hybrids are heterozygous at every locus (provided that the parental strains have different alleles). As is the case with inbred strains, they are genetically and phenotypically uniform. They are not as sensitive to environmental factors as their parent strains.

CSJLF1/JRj are more sensitive to EAE* (90-100%) than the parental BALB/c (30%-70%) strain. The mortality rate is higher than 50% one week after disease onset (Cua et al., 1999).

* Experimental Autoimmune Encephalomyelitis

Our added value

  • The « JANVIER LABS Genetic Policy », a specific programme, guarantees the genetic repeatability of our hybrid models.
  • Animals with the SPF or SOPF standards.
  • A gentling policy for docile and easy-to-handle animals.
  • Optimal stability conditions of our models during shipments, thanks to our dedicated and internal transport service.
  • A scientific support with a team of Veterinarians and PhD.

Download the corresponding health monitoring reports

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