Research models

List of models

Nomenclature: BALB/cAnNRj

Type: Inbred mouse
Colour and related genotype: Albino mouse,Tyrc/Tyrc, Tyrp1b/Tyrp1b, A/A - MHC: Haplotype H2d
Origin: National Institutes of Health (USA) - 1996 (F184)
Breeding: Good breeder with better performances than BALB/cJRj mice

Fields of research

  • Cardiovascular research
  • Immunology: ascites production, monoclonal antibodies
  • Inflammation
  • Neurobiology
  • Oncology
  • Parasitology
  • Toxicology
  • Transgenesis: embryo production

Description of our model

This strain was selected by MacDOWELL from an albino outbred stock and then sent to Dr SNELL (The Jackson Laboratory) in 1935 (generation F26). The "c" was added by Dr SNELL to indicate that the genotype at the colour locus was c/c (albinism). In 1935, Dr SNELL sent breeders to Drs HESTON an ANDERVONT at the NIH.
Dr ANDERVONT’s substrain was incorporated into NIH main colonies in 1951. BALB/cAnNRj mice achieve better ascites production than other strains derived from Dr ANDERVONT’s.

BALB/cAnNRj mice can show ulcerative blepharitis and periorbital abscesses. They can also present with hydrocephalus and malocclusion. Due to its good breeding performance, this strain is used in the production of embryos for transgenesis (QUICKBLASTO®). The QUICKBLASTO®, a JANVIER LABS's product, is a kit containing straws of frozen embryos at the morula stage (C57BL/6NRj or BALB/cAnNRj). With these embryos, after thawing and culture, you will have blastocysts ready to receive your embryonic stem cells.

Our added value

  • The « JANVIER LABS Genetic Policy », a specific programme, guarantees homozygosity of autosomal pairs.
  • Animals with the SPF or SOPF standards.
  • A gentling policy for docile and easy-to-handle animals.
  • Optimal stability conditions of our models during shipments, thanks to our dedicated and internal transport service.
  • A scientific support with a team of Veterinarians and PhD.

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