Research models

List of models

Nomenclature: BALB/cJRj

Type: Inbred mouse
Colour and related genotype: Albino mouse, Tyrc/Tyrc, Tyrp1b/Tyrp1b, A/A - MHC: Haplotype H2d
Origin: Zentralinstitut für Versuchstierzucht (Hannover) - 1988 (F172)
Breeding: Difficult to rear

Fields of research

  • Cardiovascular research
  • Immunology: ascites production, monoclonal antibodies
  • Inflammation
  • Neurology
  • Oncology
  • Parasitology
  • Virology

Description of our model

The strain was selected by MacDowell from a stock of outbred albino mice then transferred to Snell (The Jackson Laboratory) at F26 in 1935. The "c" was added to the strain name by Dr Snell to indicate that the genotype for the colour locus is c/c, hence the name BALB/c.
1935: From Dr Snell to Drs Heston and Andervont (NIH), separation of the BALB/cJ and BALB/cByJ strains at the F38 generation, when some of Dr Snell’s BALB/cSn mice were transferred to Drs Andervont and Heston. 1974: Breeders were transferred to the Production Department of The Jackson Laboratory at F136 and the J was added.

BALB/cJRj can suffer from ulcerative blepharitis and periocular abscesses. They can also present with hydrocephalus and malocclusion.

Our added value

  • The « JANVIER LABS Genetic Policy », a specific programme, guarantees homozygosity of autosomal pairs.
  • Animals with the SPF or SOPF standards.
  • A gentling policy for docile and easy-to-handle animals.
  • Optimal stability conditions of our models during shipments, thanks to our dedicated and internal transport service.
  • A scientific support with a team of Veterinarians and PhD.

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