B6 hCA4 Mouse
GEM
Model characteristics
Strain name:
C57BL/6Smoc-Car4tm1(CA4)/SmocRj
Type :
GEM
Origin:
SMOC 2026
Colour and related genotype
Black mouse
Performance de reproduction :
In vivo
Description of our model and application areas
B6 hCA4
The B6 hCA4 model carries the human carbonic anhydrase IV sequence replacing the murine counterpart.
It is designed to assess species-specific pharmacology, antibody binding, and safety of CA4-targeting molecules.
Maintained on a stable C57BL/6 background, it ensures reproducibility in renal, pulmonary, and vascular research applications.
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