from ♀ C57BL/6JRj and ♂ SJL/JRj (from JANVIER LABS)
Colour and related genotype:
Agouti mouse, A/a, Tyrc/+, p/+, Pde6brd1/+ - MHC: Haplotype H2b/s
Easy to rear, good maternal instinct
Description of our model and application areas
These F1 hybrids are the result of a cross between a C57BL/6JRj female and a SJL/JRj male. F1 hybrids are heterozygous at every locus (provided that the parental strains have different alleles). As is the case with inbred strains, they are genetically and
F1 hybrids are often used for their hybrid vigour (resistance and acitivity). They are especially interesting as genetic background (vigour and repeatability of genetic inheritance) for harmful phenotype models, for tissue transplantation, to determine mechanisms of inheritance, to create or improve expression of polygenic disease.
It is also used in behavioural studies, radiation, safety and efficacy testing for nutrients, medicine, pathogens or hormones.
Main application and research fields
Mating: ♀ C57BL/6JRj x ♂ SJL/JRj
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