NXG ILIX Mouse
Immunodeficient Mouse
Model characteristics
Strain name:
NOD-Prkdcscid-Il2rgem1Smoc-Tg(IL3, CSF2)Smoc/SmocRj
Type:
Inbred mutated mouse
Origin:
SMOC, 2024
Colour and related genotype:
Albino mouse
Performance de reproduction :
In vivo
Description of our model and application areas
𝗡𝗫𝗚 𝗜𝗟𝗜𝗫: 𝗘𝗻𝗵𝗮𝗻𝗰𝗲𝗱 𝗠𝘆𝗲𝗹𝗼𝗶𝗱 𝗮𝗻𝗱 𝗜𝗻𝗻𝗮𝘁𝗲 𝗜𝗺𝗺𝘂𝗻𝗶𝘁𝘆
Humanized for IL-3 and GM-CSF, the NXG ILIX model supports robust development of myeloid lineages post-HSPC engraftment:
🔹 Monocytes, macrophages, dendritic cells, granulocytes
🔹 Optimized for myeloid-driven inflammation, CRS, and innate immunity studies
🔹 Built on the ultra-permissive NXG background for improved engraftment
Main application and research fields
Useful documents
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