NXG MHC DKO Mouse
GEM
Model characteristics
Strain name:
NOD-Prkdcscid-H2-K1b-tm1-H2-Ab1
Type :
GEM
Origin:
JANVIER LABS, 2026
Colour and related genotype
Albino mouse
Performance de reproduction :
In vivo
Description of our model and application areas
NXG MHC DKO
Based on the NXG mouse background, the NXG MHC DKO lacks both murine MHC class I and II expression.
This dual knockout improves human immune cell engraftment by reducing xenogeneic antigen presentation.
It is optimized for advanced humanization studies in immuno-oncology and cell therapy research.
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