Zentralinstitut für Versuchstierzucht (Hannover) - 1988 (F172)
Colour and related genotype:
Albino mouse, Tyrc/Tyrc, Tyrp1b/Tyrp1b, A/A - MHC: Haplotype H2d
Difficult to rear
Description of our model and application areas
The strain was selected by MacDowell from a stock of outbred albino mice then transferred to Snell (The Jackson Laboratory) at F26 in 1935. The “c” was added to the strain name by Dr Snell to indicate that the genotype for the colour locus is c/c, hence the name BALB/c. 1935: From Dr Snell to Drs Heston and Andervont (NIH), separation of the BALB/cJ and BALB/cByJ strains at the F38 generation, when some of Dr Snell’s BALB/cSn mice were transferred to Drs Andervont and Heston. 1974: Breeders were transferred to the Production Department of The Jackson Laboratory at F136 and the J was added.
BALB/cJRj can suffer from ulcerative blepharitis and periocular abscesses. They can also present with hydrocephalus and malocclusion.
Main application and research fields
Biochemical and hematological parameters
of 10-week old BALB/cJRj mice
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