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Fischer F344 Rat

Model characteristics

Type:

Inbred rat

Strain name:

F344/HanZtmRj


Origin:

Zentralinstitut für Versuchstierzucht (Hannover) - 2013

Colour and related genotype:

Albino rat - Tyrc/Tyrc

Breeding:

Easy to rear


Cryo
In vivo
In vitro

Description of our model and application areas

This strain, the F344, was selected by Curtis and Dunning in 1920 at the Columbia University Institute for Cancer Research. Then it was acquired by a breeder FISCHER then transmitted to Heston in 1949 and at the NIH in 1951.

The F344 rat does not present any deficient activity of the Dipeptidyl peptidase-4 (DPP4), also known as adenosine deaminase complexing protein 2 or CD26, in contrary to other sublines.

Main application and research fields

Degenerative diseases, ageeing Oncology Physiology - Physiopathology Preclinical

Useful documents

Download the technical sheet

picto télécharger

Health monitoring report

Growth curve

The growth curve represents an average which reflects the weight variation of the strain measured between 21 and 84 days for males and females.

Reproductive data

Monogamous mating

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