Fischer F344 Rat
Model characteristics
Type:
Inbred rat
Strain name:
F344/HanZtmRj
Origin:
Zentralinstitut für Versuchstierzucht (Hannover) - 2013
Colour and related genotype:
Albino rat - Tyrc/Tyrc
Breeding:
Easy to rear
Cryo
In vivo
In vitro
Description of our model and application areas
This strain, the F344, was selected by Curtis and Dunning in 1920 at the Columbia University Institute for Cancer Research. Then it was acquired by a breeder FISCHER then transmitted to Heston in 1949 and at the NIH in 1951.
The F344 rat does not present any deficient activity of the Dipeptidyl peptidase-4 (DPP4), also known as adenosine deaminase complexing protein 2 or CD26, in contrary to other sublines.
Main application and research fields
Growth curve
The growth curve represents an average which reflects the weight variation of the strain measured between 21 and 84 days for males and females.
Reproductive data
Monogamous mating
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